Summary: This work establishes or suggests three things: (1) Proteasome condensate/granule formation in the cytoplasm of budding yeast often involves but does not require the shuttle factors Rad23 (human homologs: RAD23A and B) or Dsk2 (human homologs hPlic-1, UBQLN). (2) Ubiquitin chains, rather than monoubiquitin, are likely key components of proteasome granules as they may allow for multivalent interactions among condensate components. (3) Carbon starvation, gradual nutrient depletion from culture, and azide treatment in log-phase cells—as separate forms of stress—might induce different proteasome condensates that rely on the shuttle factors, ubiquitin chains, and proteasome-intrinsic ubiquitin receptors differently.